Article
Chronic intermittent mental stress promotes atherosclerotic plaque vulnerability, myocardial infarction and sudden death in mice.
Atherosclerosis - 1 Sept 2015
Roth Lynn, Rombouts Miche, Schrijvers Dorien M, Lemmens Katrien, De Keulenaer Gilles W, Martinet Wim, De Meyer Guido R Y
Abstract excerpt
Vulnerable atherosclerotic plaques are prone to plaque rupture leading to acute cardiovascular syndromes and death. Elucidating the risk of plaque rupture is important to define better therapeutic or preventive strategies. In the present study, we investigated the effect of chronic intermittent mental stress on atherosclerotic plaque stability and cardiovascular mortality in apolipoprotein E-deficient (ApoE(-/-))...
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