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Article

Thr92Ala polymorphism of human type 2 deiodinase gene (hD2) affects the development of Graves' disease, treatment efficiency, and rate of remission.

Clinical & developmental immunology - 1 Jan 2012

Alina Babenko, Daria Popkova, Olga Freylihman, Vladislav Solncev, Anna Kostareva, Elena Grineva

Abstract excerpt

Clinical symptoms vary in thyrotoxicosis, and severity of these depends on many factors. Over the last years, impact of genetic factors upon the development and clinical significance of thyrotoxic symptoms became evident. It is known that a production of T3 in various tissues is limited by deiodinase 2 (D2). Recent studies revealed that certain single nucleotide polymorphisms (including threonine (Thr) to alanine...

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Identifiers

PMID: 23193417
DOI: 10.1155/2012/340542
PMCID: PMC3502840

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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