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Article

The Type 2 Deiodinase Thr92Ala Polymorphism Is Associated with Worse Glycemic Control in Patients with Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis.

Journal of diabetes research - 1 Jan 2016

Zhang Xiaowen, Sun Jie, Han Wenqing, Jiang Yaqiu, Peng Shiqiao, Shan Zhongyan, Teng Weiping

Abstract excerpt

Objective. Type 2 deiodinase (Dio2) is an enzyme responsible for the conversion of T4 to T3. The Thr92Ala polymorphism has been shown related to an increased risk for developing type 2 diabetes mellitus (T2DM). The aim of this study is to assess the association between this polymorphism and glycemic control in T2DM patients as marked by the HbA1C levels. Design and Methods. The terms "rs225014," "thr92ala,"...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 27777960
DOI: 10.1155/2016/5928726
PMCID: PMC5061950

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