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Article

Type 2 deiodinase Thr92Ala polymorphism impact on clinical course and myocardial remodeling in patients with Graves' disease.

Cell cycle (Georgetown, Tex.) - 15 Aug 2009

Grineva Elena, Babenko Alina, Vahrameeva Natalya, Bogdanova Maria, Kostareva Anna, Popcova Daria, Larionova Valentina

Abstract excerpt

Patients with thyreotoxicosis have variable clinical manifestations and various degree of cardiomyopathy which severity depends on many factors. Last years the genetic factors predicting development and clinical features of thyrotoxic symptoms and thyreotoxic cardiomyopathy became more evident. I...

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Source

Identifiers

PMID: 19684474
DOI: 10.4161/cc.8.16.9250

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19684474-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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Type 2 deiodinase Thr92Ala polymorphism impact on clinical course and myocardial remodeling in patients with Graves' disease.PMID 19684474Read ↗

Thr92Ala polymorphism of human type 2 deiodinase gene (hD2) affects the development of Graves' disease, treatment efficiency, and rate of remission.Semantic proximity Read ↗

The Type 2 Deiodinase Thr92Ala Polymorphism Is Associated with Higher Body Mass Index and Fasting Glucose Levels: A Systematic Review and Meta-Analysis.Semantic proximity Read ↗

No Effect of the Thr92Ala Polymorphism of Deiodinase-2 on Thyroid Hormone Parameters, Health-Related Quality of Life, and Cognitive Functioning in a Large Population-Based Cohort Study.Semantic proximity Read ↗

The Physiological Functions and Polymorphisms of Type II DeiodinaseSemantic proximity Read ↗

Association of the type 2 deiodinase Thr92Ala polymorphism with type 2 diabetes: case-control study and meta-analysis.Semantic proximity Read ↗

Ala92 type 2 deiodinase allele increases risk for the development of hypertension.Semantic proximity Read ↗

Association Between a Novel Variant of the Human Type 2 Deiodinase Gene Thr92Ala and Insulin ResistanceSemantic proximity Read ↗

Prevalent polymorphism in thyroid hormone-activating enzyme leaves a genetic fingerprint that underlies associated clinical syndromes.Semantic proximity Read ↗

DIO2 Thr92Ala Reduces Deiodinase-2 Activity and Serum-T3 Levels in Thyroid-Deficient Patients.Semantic proximity Read ↗

Polymorphisms of β 1-adrenoreceptor gene and cardiovascular complications in patients with thyrotoxicosis.Semantic proximity Read ↗

The role of type II deiodinase polymorphisms in clinical management of hypothyroid patients treated with levothyroxine.Semantic proximity Read ↗

Prevalence of Dio2(T92A) polymorphism and its association with thyroid autoimmunity.Semantic proximity Read ↗

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