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Article

[Comparison of real-time PCR-optimized oligonucleotide probe method and Sanger sequencing for detection of KRAS mutations in colorectal and lung carcinomas].

Zhonghua bing li xue za zhi = Chinese journal of pathology - 1 Sept 2012

Qiu Tian, Ling Yun, Chen Zhao, Shan Ling, Guo Lei, Lü Ning, Ying Jian-ming

Abstract excerpt

OBJECTIVE: To investigate the feasibility of real-time PCR-optimized oligonucleotide probe method for detection of KRAS mutations in lung and colorectal carcinomas, as compared with Sanger sequencing method. METHODS: Genomic DNA was extracted from formalin fixed paraffin embedded samples of 221 lung carcinomas and 131 colorectal carcinomas after tumor cell content assessment and macrodissection. Real-time...

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Source

Identifiers

PMID: 23157827
DOI: 10.3760/cma.j.issn.0529-5807.2012.09.006

Genes

KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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