Article
[Detection of epidermal growth factor receptor gene mutation in non-small cell lung cancer by allele-specific oligonucleotide-PCR and bi-loop probe specific primer quantitative PCR].
Zhonghua bing li xue za zhi = Chinese journal of pathology - 1 Jan 2012
Deng Lei, Tang Yuan, Lin Jing, Lu Xiao-jun, Xue Jian-xin, Wang Li-shuai, Zhou Lin, Zou Yan, Ying Bin-wu, Li Gan-di, Lu You
Abstract excerpt
OBJECTIVE: To compare the detection sensitivity of epidermal growth factor receptor (EGFR) mutations between allele specific oligonucleotide PCR (ASO-PCR) and bi-loop probe and specific primer quantitative PCR (BPSP-qPCR). METHODS: A total of 96 non-small cell lung cancer specimens were selected from West China Hospital from September 2009 to December 2010. ASO-PCR was developed to detect the presence of...
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