Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[Detection of KRAS, BRAF, PIK3CA and EGFR gene mutations in colorectal carcinoma].

Zhonghua bing li xue za zhi = Chinese journal of pathology - 1 Sept 2012

Ling Yun, Ying Jian-ming, Qiu Tian, Shan Ling, Guo Lei, Lü Ning

Abstract excerpt

OBJECTIVE: To investigate the mutation frequencies of KRAS, BRAF, PIK3CA and EGFR genes that were effective on the targeted therapies in colorectal carcinoma. METHODS: The tissue specimens from 331 colorectal cancer patients were collected and subject to KRAS, BRAF, PIK3CA and EGFR mutation analysis. Paraffin-embedded tissue samples were obtained and macrodissection was performed to enrich the tumor cells for DNA...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Class I Phosphatidylinositol 3-Kinases
Share to Codon

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to ErbB Receptors

Share to Phosphatidylinositol 3-Kinases

Share to Proto-Oncogene Proteins

Share to Proto-Oncogene Proteins B-raf

Share to Proto-Oncogene Proteins p21(ras)

Share to ras Proteins

Source

Identifiers

PMID: 23157825
DOI: 10.3760/cma.j.issn.0529-5807.2012.09.004

Genes

KRAS
BRAF
EGFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[Detection of KRAS, BRAF, PIK3CA and EGFR gene mutations in colorectal carcinoma].PMID 23157825Read ↗

[Detection of KRAS,NRAS and BRAF gene mutations in colorectal carcinoma].Semantic proximity Read ↗

[KRAS mutation test].Semantic proximity Read ↗

[Detection of KRAS gene mutation and its clinical significance in colorectal adenocarcinoma].Semantic proximity Read ↗

[Detection of KRAS gene mutations in colorectal carcinoma: a study of 6 364 patients].Semantic proximity Read ↗

[The frequency and spectrum of KRAS mutations in metastatic colorectal cancer].Semantic proximity Read ↗

[Clinical-pathological features and gene profile in colorectal cancer].Semantic proximity Read ↗

[The role of KRAS gene mutation testing in colorectal cancer--a predictive biomarker of response to EGFR inhibitors therapy].Semantic proximity Read ↗

A Systematic Review and Meta-analysis on the Occurrence of Biomarker Mutation in Colorectal Cancer among the Asian Population.Semantic proximity Read ↗

[Correlation between KRAS mutations and clinicopathologic features in colorectal carcinomas].Semantic proximity Read ↗

[Relationship between KRAS gene mutation sites and clinical characteristics in colorectal cancer].Semantic proximity Read ↗

[Screening for K-ras mutations in colorectal and lung cancers by using a novel real-time PCR with ADx-K-ras kit and Sanger DNA sequencing].Semantic proximity Read ↗

Targeting KRAS G12C Mutation in Colorectal Cancer, A Review: New Arrows in the Quiver.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.