Article
[Epidermal growth factor receptor gene mutations and clinicopathologic correlation in 309 patients with non-small cell lung cancer].
Zhonghua bing li xue za zhi = Chinese journal of pathology - 1 Oct 2011
Feng Qin, Li Xiang-hong, Chen Zhao, He Jing-sheng, Wang Chun-xu, Zhou Li-xin, Xue Wei-cheng
Abstract excerpt
OBJECTIVE: To investigate the epidermal growth factor receptor (EGFR) gene mutation profile and related clinicopathological features in Chinese patients with non-small cell lung carcinoma (NSCLC). METHODS: Optimized oligonucleotide probe method was applied to detect EGFR mutations involving exons 18 - 21 using formalin fixed paraffin embedded tissue specimens of 309 NSCLC patients. The relationship between EGFR...
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