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Article

Cubic regression-based degree of correction predicts the performance of whole bisulfitome amplified DNA methylation analysis.

Epigenetics - 1 Dec 2012

Fernandez-Jimenez Nora, Plaza-Izurieta Leticia, Lopez-Euba Tamara, Jauregi-Miguel Amaia, Ramon Bilbao Jose

Abstract excerpt

Epigenetic mechanisms, including DNA methylation, are important determinants in development and disease. There is a need for technologies capable of detecting small variations in methylation levels in an accurate and reproducible manner, even if only limited amounts of DNA are available (which is the case in many studies in humans). Quantitative methylation analysis of minute DNA amounts after whole bisulfitome...

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PMID: 23154537
DOI: 10.4161/epi.22846
PMCID: PMC3528690

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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