Article
Comparative analysis of methods to determine DNA methylation levels of a tumor-related microRNA gene.
Analytical biochemistry - 1 Sept 2015
Konishi Yuki, Hayashi Hiroshi, Suzuki Hiromu, Yamamoto Eiichiro, Sugisaki Hajime, Higashimoto Hiroko
Abstract excerpt
Quantifying levels of DNA methylation in tumors is a useful approach for the identification of potential tumor suppressors and to find biomarkers that can be used as prognostic or therapeutic indicators. In the current study, we compared three methods commonly used for quantifying DNA methylation-bisulfite pyrosequencing, quantitative methylation-specific PCR (Q-MSP), and MethyLight-by focusing on the CpG island...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
