Article

Quantitative methylation reference datasets of Quartet DNA reference materials for benchmarking genome-wide epigenome sequencing

2025-05-09

Abstract excerpt

<title>Abstract</title> The absence of cross-lab and cross-replicate reproducibility assessments and the lack of quantitative methylation reference datasets (ground truth) impedes benchmarking genome-wide epigenome sequencing for its intended use in clinical settings such as disease diagnostics and prognostics. Using the four Quartet DNA reference materials, we generated cross-lab epigenome sequencing datasets...

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Literature Corpus work: 30129517-6109-580a-a8ee-5ab41cc34399
DOI: 10.21203/rs.3.rs-6420165/v1

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