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Article

Py2T murine breast cancer cells, a versatile model of TGFβ-induced EMT in vitro and in vivo.

PloS one - 1 Jan 2012

Waldmeier Lorenz, Meyer-Schaller Nathalie, Diepenbruck Maren, Christofori Gerhard

Abstract excerpt

INTRODUCTION: Increasing evidence supports a role of an epithelial to mesenchymal transition (EMT) process in endowing subsets of tumor cells with properties driving malignant tumor progression and resistance to cancer therapy. To advance our understanding of the underlying mechanisms, we sought to generate a transplantable cellular model system that allows defined experimental manipulation and analysis of EMT in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23144919
DOI: 10.1371/journal.pone.0048651
PMCID: PMC3492491

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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