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Tumor Heterogeneity and Cooperating Cancer Hallmarks Driven by Divergent EMT Programs

15 Nov 2024

Abstract excerpt

Epithelial-to-mesenchymal transition (EMT) is known to play roles in orchestrating cellular plasticity across many physiological and pathological contexts. Partial EMT, wherein cells maintain both epithelial and mesenchymal features, is gaining recognition for its functional importance in cancer in recent years. There are many factors regulating both partial and full EMT, and the precise mechanisms underlying...

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PMID: 39546766
DOI: 10.1158/0008-5472.can-24-4309

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