Article

Construction of an Improved Orthotopic Transplantation Model of Breast Cancer and Study of Tumor Metastasis Mechanisms

2026-06-30

Abstract excerpt

<title>Abstract</title> <p> Objective To address the long timeline, high cost, narrow metastatic spectrum, and extensive intra-group heterogeneity of the spontaneous MMTV-PyMT breast cancer mouse model, this study constructed an improved, cryopreservable orthotopic transplantation model suitable for mass production. We evaluated its metastatic characteristics and molecular regulatory mechanisms to provide an ef...

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Literature Corpus work: b59c71c8-1806-5d0c-8e12-71feae5dde8a
DOI: 10.21203/rs.3.rs-9859014/v1

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