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Insights from transgenic mouse models of PyMT-induced breast cancer: recapitulating human breast cancer progression in vivo

24 Nov 2020

Abstract excerpt

Breast cancer is associated with the second highest cancer-associated deaths worldwide. Therefore, understanding the key events that determine breast cancer progression, modulation of the tumor-microenvironment and metastasis, which is the main cause of cancer-associated death, are of great importance. The mammary specific polyomavirus middle T antigen overexpression mouse model (MMTV-PyMT), first published in...

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PMID: 33235291
DOI: 10.1038/s41388-020-01560-0

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