The effects of the catechol-O-methyltransferase val158met polymorphism on white matter connectivity in patients with panic disorder.

doi:10.1016/j.jad.2012.10.009

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Article

The effects of the catechol-O-methyltransferase val158met polymorphism on white matter connectivity in patients with panic disorder.

Journal of affective disorders - 1 May 2013

Kim Borah, Yoo Eunhye, Lee Jun-Yeob, Lee Kang Soo, Choe Ah Young, Lee Ji Eun, Kwack Kyubum, Yook Ki-Hwan, Choi Tai Kiu, Lee Sang-Hyuk

Abstract excerpt

BACKGROUND: The catechol-O-methyltransferase (COMT) gene val158met polymorphism (rs4680) has been found to be associated with various psychiatric phenotypes including panic disorder. Considering the probable genetic influence of COMT on the pathogenesis of panic disorder and white matter connectivity, the present study investigated white matter connectivity using diffusion tensor imaging in relation to the COMT...

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Identifiers

PMID: 23141115
DOI: 10.1016/j.jad.2012.10.009

Genes

COMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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