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Article

Effect of the COMT val158met polymorphism on white matter connectivity in patients with major depressive disorder.

Neuroscience letters - 17 Jun 2013

Seok Jeong-Ho, Choi Sunyoung, Lim Hyun Kook, Lee Sang-Hyuk, Kim InSeong, Ham Byung-Joo

Abstract excerpt

Cortico-limbic network dysfunction and genetic polymorphism are considered to be associated with major depressive disorder (MDD). Using diffusion tensor imaging (DTI), we investigated the relationship between catechol-O-methyltransferase (COMT) gene polymorphisms and white matter tract integrity in patients with MDD. Eighty-six patients with MDD and 62 healthy controls participated in this study. DTI and...

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Source

Identifiers

PMID: 23618651
DOI: 10.1016/j.neulet.2013.04.012

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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