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Article

Meta-analysis of COMT val158met in panic disorder: ethnic heterogeneity and gender specificity.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Jul 2007

Domschke Katharina, Deckert Juergen, O'donovan Michael C, Glatt Stephen J

Abstract excerpt

There is strong evidence for a genetic contribution to the pathogenesis of panic disorder, with the functional catechol-O-methyltransferase (COMT) val158met polymorphism having been suggested as a potential susceptibility factor. In the present study, a meta-analysis of six available case-control studies (557 patients with panic disorder and 763 healthy controls in total) on the role of the COMT val158met...

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Source

Identifiers

PMID: 17357147
DOI: 10.1002/ajmg.b.30494

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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