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Article

The catechol-o-methyltransferase Val¹⁵⁸Met polymorphism modulates the intrinsic functional network centrality of the parahippocampal cortex in healthy subjects.

Scientific reports - 9 Jun 2015

Zhang Xiaolong, Li Jin, Qin Wen, Yu Chunshui, Liu Bing, Jiang Tianzi

Abstract excerpt

The influence of catechol-o-methyltransferase (COMT) Val(158)Met on brain activation and functional connectivity has been widely reported. However, voxel-wise effects of this genotype on resting-state brain networks remain unclear. Here, we used resting-state fMRI and eigenvector centrality to examine the effects of COMT Val(158)Met genotypes on the connection patterns of the brain network and working memory (WM)...

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Share to Catechol O-Methyltransferase
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26054510
DOI: 10.1038/srep10105
PMCID: PMC4460568

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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