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Article

Association of the Val158Met catechol O-methyltransferase genetic polymorphism with panic disorder.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Oct 2006

Rothe Claudia, Koszycki Diana, Bradwejn Jacques, King Nicole, Deluca Vincenzo, Tharmalingam Subi, Macciardi Fabio, Deckert Jürgen, Kennedy James L

Abstract excerpt

Genetic as well as clinical data suggest that catechol O-methyltransferase (COMT) is involved in multiple complex psychiatric conditions. Recent studies have described an association between the Val158Met COMT polymorphism and panic disorder. Other recent investigations provide evidence that there are other loci within or nearby the COMT gene that may contribute to the susceptibility to panic disorder. To further...

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Source

Identifiers

PMID: 16525418
DOI: 10.1038/sj.npp.1301048

Genes

COMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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