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Article

Catechol-O-methyltransferase Val158Met polymorphism modulates gray matter volume and functional connectivity of the default mode network.

PloS one - 1 Jan 2013

Tian Tian, Qin Wen, Liu Bing, Wang Dawei, Wang Junping, Jiang Tianzi, Yu Chunshui

Abstract excerpt

The effect of catechol-O-methyltransferase (COMT) Val158Met polymorphism on brain structure and function has been previously investigated separately and regionally; this prevents us from obtaining a full picture of the effect of this gene variant. Additionally, gender difference must not be overl...

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Identifiers

PMID: 24147141
DOI: 10.1371/journal.pone.0078697
PMCID: PMC3797700

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24147141-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Catechol-O-methyltransferase Val158Met polymorphism modulates gray matter volume and functional connectivity of the default mode network.PMID 24147141Read ↗

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Genetic Variation in the Catechol-O-Methyl Transferase Val108/158Met Is Linked to the Caudate and Posterior Cingulate Cortex Volume in Healthy Subjects: Voxel-Based Morphometry Analysis of Brain Magnetic Resonance Imaging.Semantic proximity Read ↗

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The catechol-o-methyltransferase Val¹⁵⁸Met polymorphism modulates the intrinsic functional network centrality of the parahippocampal cortex in healthy subjects.Semantic proximity Read ↗

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