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Article

Intestinal master transcription factor CDX2 controls chromatin access for partner transcription factor binding.

Molecular and cellular biology - 1 Jan 2013

Verzi Michael P, Shin Hyunjin, San Roman Adrianna K, Liu X Shirley, Shivdasani Ramesh A

Abstract excerpt

Tissue-specific gene expression requires modulation of nucleosomes, allowing transcription factors to occupy cis elements that are accessible only in selected tissues. Master transcription factors control cell-specific genes and define cellular identities, but it is unclear if they possess special abilities to regulate cell-specific chromatin and if such abilities might underlie lineage determination and...

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Source

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Identifiers

PMID: 23129810
DOI: 10.1128/MCB.01185-12
PMCID: PMC3554120

Genes

CDX2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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