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Article

HNF4 factors control chromatin accessibility and are redundantly required for maturation of the fetal intestine

25 Jul 2019

Abstract excerpt

ABSTRACT As embryos mature, cells undergo remarkable transitions that are accompanied by shifts in transcription factor regulatory networks. Mechanisms driving developmental transitions are incompletely understood. The embryonic intestine transitions from a rapidly proliferating tube with pseudostratified epithelium prior to murine embryonic day (E) 14.5 to an exquisitely folded columnar epithelium in fetal...

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PMID: 31345929
DOI: 10.1242/dev.179432

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