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Article

Clinical feature of anaplastic lymphoma kinase-mutated neuroblastoma.

Journal of pediatric surgery - 1 Oct 2012

Ogura Taemi, Hiyama Eiso, Kamei Naomi, Kamimatsuse Arata, Ueda Yuka, Ogura Kaoru

Abstract excerpt

PURPOSE: Anaplastic lymphoma kinase (ALK) has recently been identified as a gene conferring a predisposition for neuroblastoma. We have analyzed tyrosine kinase domain mutations and amplification/expression of the ALK gene and focused on clinical features of neuroblastoma cases with ALK aberrations. METHODS: The frequency of ALK mutations, copy number gain, and expression were analyzed in 538 neuroblastoma tumors...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23084186
DOI: 10.1016/j.jpedsurg.2012.05.007

Genes

ALK
MYC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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