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Article

Anaplastic Lymphoma Kinase as a Cancer Target in Pediatric Malignancies.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Feb 2016

Mossé Yael P

Abstract excerpt

In this era of more rational therapies, substantial efforts are being made to identify optimal targets. The discovery of translocations involving the anaplastic lymphoma kinase (ALK) receptor tyrosine kinase in a subset of non-small cell lung cancers has become a paradigm for precision medicine. Notably, ALK was initially discovered as the fusion gene in anaplastic large cell non-Hodgkin lymphoma, a disease...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26503946
DOI: 10.1158/1078-0432.CCR-14-1100
PMCID: PMC4738092

Genes

ALK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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