Article
Identification of ALK Mutation in Neuroblastoma on the Point of Molecular Heterogeneity.
Technology in cancer research & treatment - 1 Jan 2000
Aktaş Tekincan Çağrı, Kızmazoğlu Deniz, Aktaş Safiye, Gökbayrak Özde Elif, Serinan Efe, Erol Aylin, Altun Zekiye, Yuan Hongling, Olgun Hatice Nur
Abstract excerpt
BACKGROUND AND AIM: In neuroblastoma, anaplastic lymphoma kinase mutations have recently received attention as molecular targets for the treatment of neuroblastoma, as 6% to 10% of patients with neuroblastoma have anaplastic lymphoma kinase mutations. There are little data from the cases in Turkey. We aimed to detect anaplastic lymphoma kinase mutations and molecular heterogeneity in neuroblastoma using...
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