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Article

15 Years Old ALK Gene from Birth to Adolescence; Where to in NBL.

Current oncology reports - 1 Apr 2025

Elmenawi Salma, Fawzy Mohamed

Abstract excerpt

PURPOSE OF REVIEW: This review provides a comprehensive understanding of the ALK gene, encompassing its prevalence, genetic alterations, and significance in neuroblastoma diagnosis, outcome prediction, and targeted therapy utilization. The insights presented aim to inform future research directions and clinical practices in this field. RECENT FINDINGS: High risk neuroblastoma, comprising approximately 50% of all...

Read the complete abstract on PubMed

Topics

Humans
Anaplastic Lymphoma Kinase
Neuroblastoma
Receptor Protein-Tyrosine Kinases
Adolescent
Mutation
Infant

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Protein Kinase Inhibitors

Infant, Newborn

Child

Molecular Targeted Therapy

Source

Open in PubMed Open full text

Identifiers

PMID: 40064818
DOI: 10.1007/s11912-025-01650-w
PMCID: PMC11976753

Genes

ALK
MYCN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

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