Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ALK in Neuroblastoma: Biological and Therapeutic Implications

10 Apr 2018

Abstract excerpt

Neuroblastoma (NB) is the most common and deadly solid tumour in children. Despite the development of new treatment options for high-risk NB, over half of patients relapse and five-year survival remains at 40–50%. Therefore, novel treatment strategies aimed at providing long-term disease remission are urgently sought. ALK, encoding the anaplastic lymphoma kinase receptor, is altered by gain-of-function point...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer, Hypoxia, and Metabolism
Share to Cancer therapeutics and mechanisms
Share to Neuroblastoma Research and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29642598
DOI: 10.3390/cancers10040113

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ALK in Neuroblastoma: Biological and Therapeutic ImplicationsPMID 29642598Read ↗

Oncogenic mutations of ALK in neuroblastoma.Semantic proximity Read ↗

Targeting anaplastic lymphoma kinase in neuroblastomaSemantic proximity Read ↗

ALK Inhibitors in Neuroblastoma: A Sprint from Bench to Bedside.Semantic proximity Read ↗

Activating mutations in ALK provide a therapeutic target in neuroblastoma.Semantic proximity Read ↗

Oncogenic mutations of ALK kinase in neuroblastoma.Semantic proximity Read ↗

Targeted Therapy for Neuroblastoma: ALK InhibitorsSemantic proximity Read ↗

Anaplastic Lymphoma Kinase as a Cancer Target in Pediatric Malignancies.Semantic proximity Read ↗

Differential Impact of ALK Mutations in Neuroblastoma.Semantic proximity Read ↗

ALK gene alterations in cancer: biological aspects and therapeutic implications.Semantic proximity Read ↗

Emerging importance of ALK in neuroblastomaSemantic proximity Read ↗

New strategies in neuroblastoma: Therapeutic targeting of MYCN and ALK.Semantic proximity Read ↗

The ALK receptor in sympathetic neuron development and neuroblastoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.