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Article

Myeloperoxidase: a front-line defender against phagocytosed microorganisms

12 Oct 2012

Abstract excerpt

Successful immune defense requires integration of multiple effector systems to match the diverse virulence properties that members of the microbial world might express as they initiate and promote infection. Human neutrophils--the first cellular responders to invading microbes--exert most of their antimicrobial activity in phagosomes, specialized membrane-bound intracellular compartments formed by ingestion of...

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Share to Immune Response and Inflammation
Share to Neutrophil, Myeloperoxidase and Oxidative Mechanisms
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PMID: 23066164
DOI: 10.1189/jlb.0712349

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