Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Neutrophil dysfunction in the pathogenesis of cystic fibrosis

25 Feb 2022

Abstract excerpt

Polymorphonuclear neutrophils (PMNs) figure prominently in host defense against infection and in noninfectious inflammation. Mobilized early in an inflammatory response, PMNs mediate immediate cellular defense against microbes and orchestrate events that culminate in cessation of inflammation and restoration of homeostasis. Failure to terminate the inflammatory response and its causes can fuel exuberant...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial biofilms and quorum sensing
Share to Cystic Fibrosis Research Advances
Share to Neutrophil, Myeloperoxidase and Oxidative Mechanisms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35213685
DOI: 10.1182/blood.2021014699

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Neutrophil dysfunction in the pathogenesis of cystic fibrosisPMID 35213685Read ↗

The Cystic Fibrosis Neutrophil: A Specialized Yet Potentially Defective CellSemantic proximity Read ↗

Neutrophils in cystic fibrosisSemantic proximity Read ↗

Dysregulated Calcium Homeostasis in Cystic Fibrosis Neutrophils Leads to Deficient Antimicrobial Responses.Semantic proximity Read ↗

Myeloperoxidase: a front-line defender against phagocytosed microorganismsSemantic proximity Read ↗

Neutrophil-Mediated Phagocytic Host Defense Defect in Myeloid Cftr-Inactivated MiceSemantic proximity Read ↗

Phagocyte oxidants and nitric oxide in cystic fibrosis: new therapeutic targets?Semantic proximity Read ↗

CFTR mutation leads to intrinsic dysfunction in neutrophils from people with Cystic FibrosisSemantic proximity Read ↗

Neutrophilic inflammation as a major determinant in the progression of cystic fibrosis.Semantic proximity Read ↗

Myeloperoxidase.Semantic proximity Read ↗

Inhibiting CFTR through inh-172 in primary neutrophils reveals CFTR-specific functional defects.Semantic proximity Read ↗

Quality control in the endoplasmic reticulum: lessons from hereditary myeloperoxidase deficiency.Semantic proximity Read ↗

The Challenges of Detecting Neutrophil CFTR.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.