The complex role of neutrophils in healthy aging, inflammaging, and frailty

Abstract excerpt

Immune function alters as we age, and is often accompanied by chronic, low-grade inflammation termed "inflammaging." This leads cells to develop a senescence-associated secretory phenotype and release a range of proinflammatory cytokines and proteolytic enzymes. In individuals with frailty, inflammaging and senescence-associated secretory phenotype are increased, further reducing immune function and making...

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• Share to Adipokines, Inflammation, and Metabolic Diseases
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• Share to Neutrophil, Myeloperoxidase and Oxidative Mechanisms