Article
Myeloperoxidase.
Current opinion in hematology - 1 Jan 2000
Winterbourn C C, Vissers M C, Kettle A J
Abstract excerpt
This review covers recent advances in the biology of myeloperoxidase. Mechanisms of posttranslational processing and how these fail in some of the common deficiency mutants are discussed. We also review the enzymology that points to myeloperoxidase having a number of physiologic substrates in addition to chloride and the evidence that it produces hypochlorous acid in the neutrophil phagosome in sufficient...
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