Article
A transgenic zebrafish line for in vivo visualisation of neutrophil myeloperoxidase
2018-10-30
Abstract excerpt
The neutrophil enzyme myeloperoxidase (MPO) is a major enzyme made by neutrophils to generate antimicrobial and immunomodulatory compounds, notably hypochlorous acid (HOCl), amplifying their capacity for destroying pathogens and regulating inflammation. Despite its roles in innate immunity, the importance of MPO in preventing infection is unclear, as individuals with MPO deficiency are asymptomatic with the except...
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Identifiers and source
- Literature Corpus work
- 6247347d-d871-5cbc-a136-bd3689f31548
- DOI
- 10.1101/456541