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Article

Myeloperoxidase is required for neutrophil extracellular trap formation: implications for innate immunity.

Blood - 20 Jan 2011

Metzler Kathleen D, Fuchs Tobias A, Nauseef William M, Reumaux Dominique, Roesler Joachim, Schulze Ilka, Wahn Volker, Papayannopoulos Venizelos, Zychlinsky Arturo

Abstract excerpt

The granule enzyme myeloperoxidase (MPO) plays an important role in neutrophil antimicrobial responses. However, the severity of immunodeficiency in patients carrying mutations in MPO is variable. Serious microbial infections, especially with Candida species, have been observed in a subset of com...

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Source

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Identifiers

PMID: 20974672
DOI: 10.1182/blood-2010-06-290171
PMCID: PMC3035083

Genes

MPO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20974672-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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