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Article

Low genetic diversity and functional constraint in loci encoding Plasmodium vivax P12 and P38 proteins in the Colombian population.

Malaria journal - 18 Feb 2014

Forero-Rodríguez Johanna, Garzón-Ospina Diego, Patarroyo Manuel A

Abstract excerpt

BACKGROUND: Plasmodium vivax is one of the five species causing malaria in human beings, affecting around 391 million people annually. The development of an anti-malarial vaccine has been proposed as an alternative for controlling this disease. However, its development has been hampered by allele-specific responses produced by the high genetic diversity shown by some parasite antigens. Evaluating these antigens'...

Topics

Antigens, Protozoan
Colombia
DNA, Protozoan
Genetic Variation
Genotype
Haplotypes
Humans
Malaria, Vivax
Molecular Sequence Data
Plasmodium vivax
Protozoan Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Sequence Analysis, DNA

Source

Open in PubMed Open full text

Identifiers

PMID: 24533461
DOI: 10.1186/1475-2875-13-58
PMCID: PMC3930544

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-24533461-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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