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Article

Low genetic diversity and functional constraint in loci encoding Plasmodium vivax P12 and P38 proteins in the Colombian population.

Malaria journal - 18 Feb 2014

Forero-Rodríguez Johanna, Garzón-Ospina Diego, Patarroyo Manuel A

Abstract excerpt

BACKGROUND: Plasmodium vivax is one of the five species causing malaria in human beings, affecting around 391 million people annually. The development of an anti-malarial vaccine has been proposed as an alternative for controlling this disease. However, its development has been hampered by allele-specific responses produced by the high genetic diversity shown by some parasite antigens. Evaluating these antigens'...

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Identifiers

PMID: 24533461
DOI: 10.1186/1475-2875-13-58
PMCID: PMC3930544

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Source receipt: pubmed, retrieved 7 Sept 2026.

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