Article
Exploration of Plasmodium vivax merozoite surface proteins 1 and 7 genetic diversity in Brazilian Amazon and Rio de Janeiro Atlantic Forest.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Dec 2020
Almeida-de-Oliveira Natália Ketrin, Abreu-Fernandes Rebecca, Lavigne Aline Rosa, Pina-Costa Anielle, Perce-da-Silva Daiana de Souza, Catanho Marcos, Rossi Átila Duque, Brasil Patrícia, Daniel-Ribeiro Cláudio Tadeu, Ferreira-da-Cruz Maria de Fátima
Abstract excerpt
Plasmodium vivax merozoite surface proteins (PvMSP) 1 and 7 are considered vaccine targets. Genetic diversity knowledge is crucial to assess their potential as immunogens and to provide insights about population structure in different epidemiological contexts. Here, we investigate the variability of pvmsp-142, pvmsp-7E, and pvmsp-7F genes in 227 samples from the Brazilian Amazon (BA) and Rio de Janeiro Atlantic...
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