Article
Causal inference of the effect of adiposity on bone mineral density in adults.
Clinical endocrinology - 1 May 2013
Warodomwichit Daruneewan, Sritara Chanika, Thakkinstian Ammarin, Chailurkit La-Or, Yamwong Sukit, Ratanachaiwong Wipa, Ongphiphadhanakul Boonsong, Sritara Piyamitr
Abstract excerpt
OBJECTIVE: The causal effect of adipose tissue on bone mass and the direction of its net influence have not been directly assessed in adult humans. Using the Mendelian randomization analysis, we assessed the causality of adiposity in measurements of bone mass in adult males and females. DESIGN AND METHODS: Subjects consisted of 2154 adults aged 25-54 years from a cross-sectional cohort of the employees of the...
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