Article
Effects of BMI, fat mass, and lean mass on asthma in childhood: a Mendelian randomization study.
PLoS medicine - 1 Jul 2014
Granell Raquel, Henderson A John, Evans David M, Smith George Davey, Ness Andrew R, Lewis Sarah, Palmer Tom M, Sterne Jonathan A C
Abstract excerpt
BACKGROUND: Observational studies have reported associations between body mass index (BMI) and asthma, but confounding and reverse causality remain plausible explanations. We aim to investigate evidence for a causal effect of BMI on asthma using a Mendelian randomization approach. METHODS AND FINDINGS: We used Mendelian randomization to investigate causal effects of BMI, fat mass, and lean mass on current asthma...
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