Article
Causal relationship between body mass index and fetuin-A level in the asian population: a bidirectional Mendelian randomization study.
Clinical endocrinology - 1 Aug 2014
Thakkinstian Ammarin, Chailurkit Laor, Warodomwichit Daruneewan, Ratanachaiwong Wipa, Yamwong Sukit, Chanprasertyothin Suwannee, Attia John, Sritara Piyamitr, Ongphiphadhanakul Boonsong
Abstract excerpt
OBJECTIVE: Fetuin-A is associated with body mass index (BMI) as well as components of the metabolic syndrome. However, it is unclear if fetuin-A affects BMI or the other way around. We therefore assessed the causal association between fetuin-A and BMI or vice versa, utilizing a bidirectional Mendelian randomization approach. DESIGN AND METHODS: This was a study of 2558 subjects from the Electricity Generating...
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