Association of obesity/visceral adipose tissue mass with bone mineral density and osteoporosis: a prospective study and Mendelian Randomization study.

Abstract excerpt

BACKGROUND AND AIM: The association between obesity and osteoporosis (OP) remains complex and elusive. We elucidated the associations and identified the mediators between obesity/visceral adipose tissue (VAT) and bone mineral density (BMD) and OP in the UK Biobank population, as well as explored the causal associations between obesity/VAT and OP. METHODS AND RESULTS: We analyzed 38,026 UK Biobank participants....

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• Adiposity
• Bone Density
• Intra-Abdominal Fat
• Mendelian Randomization Analysis
• Osteoporosis