Article
The Relationship Between Body Mass Index and Bone Mineral Density: A Mendelian Randomization Study.
Calcified tissue international - 1 Nov 2020
Song Jidong, Zhang Rupeng, Lv Leifeng, Liang Jialin, Wang Wei, Liu Ruiyu, Dang Xiaoqian
Abstract excerpt
Body mass index (BMI) is closely associated with bone mineral density (BMD) in both men and women. However, the relationship between BMI and BMD varies according to different studies. Using SNPs strongly associated with BMI in 336,107 individuals, we conducted a two-sample Mendelian randomization study to identify whether and to what extent BMD at different skeletal sites was affected by BMI. A power calculation...
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