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Article

The C-terminus of Dpb2 is required for interaction with Pol2 and for cell viability.

Nucleic acids research - 1 Dec 2012

Isoz Isabelle, Persson Ulf, Volkov Kirill, Johansson Erik

Abstract excerpt

DNA polymerase ε (Pol ε) participates in the synthesis of the leading strand during DNA replication in Saccharomyces cerevisiae. Pol ε comprises four subunits: the catalytic subunit, Pol2, and three accessory subunits, Dpb2, Dpb3 and Dpb4. DPB2 is an essential gene with unclear function. A genetic screen was performed in S. cerevisiae to isolate lethal mutations in DPB2. The dpb2-200 allele carried two mutations...

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PMID: 23034803
DOI: 10.1093/nar/gks880
PMCID: PMC3526264

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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