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Article

Defective interaction between Pol2p and Dpb2p, subunits of DNA polymerase epsilon, contributes to a mutator phenotype in Saccharomyces cerevisiae.

Mutation research - 2 Oct 2009

Jaszczur Malgorzata, Rudzka Justyna, Kraszewska Joanna, Flis Krzysztof, Polaczek Piotr, Campbell Judith L, Fijalkowska Iwona J, Jonczyk Piotr

Abstract excerpt

Most of the prokaryotic and eukaryotic replicative polymerases are multi-subunit complexes. There are several examples indicating that noncatalytic subunits of DNA polymerases may function as fidelity factors during replication process. In this work, we have further investigated the role of Dpb2p, a noncatalytic subunit of DNA polymerase epsilon holoenzyme from Saccharomyces cerevisiae in controlling the level of...

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Identifiers

PMID: 19463834
DOI: 10.1016/j.mrfmmm.2009.04.012
PMCID: PMC2771212

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Defective interaction between Pol2p and Dpb2p, subunits of DNA polymerase epsilon, contributes to a mutator phenotype in Saccharomyces cerevisiae.PMID 19463834Read ↗

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