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Article

DPB2, the gene encoding DNA polymerase II subunit B, is required for chromosome replication in Saccharomyces cerevisiae.

Proceedings of the National Academy of Sciences of the United States of America - 1 Jun 1991

Araki H, Hamatake R K, Johnston L H, Sugino A

Abstract excerpt

The Saccharomyces cerevisiae DNA polymerase II holoenzyme consists of five polypeptides. The largest is the catalytic subunit, whose gene (POL2) has been cloned and sequenced. Herein we describe the cloning and sequencing of DPB2, the gene for the second largest subunit of DNA polymerase II, and the isolation of temperature-sensitive dpb2 mutations. The DNA sequence revealed an open reading frame encoding a...

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Identifiers

PMID: 2052544
DOI: 10.1073/pnas.88.11.4601
PMCID: PMC51713

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