Article
Dpb11, which interacts with DNA polymerase II(epsilon) in Saccharomyces cerevisiae, has a dual role in S-phase progression and at a cell cycle checkpoint.
Proceedings of the National Academy of Sciences of the United States of America - 5 Dec 1995
Araki H, Leem S H, Phongdara A, Sugino A
Abstract excerpt
DPB11, a gene that suppresses mutations in two essential subunits of Saccharomyces cerevisiae DNA polymerase II(epsilon) encoded by POL2 and DPB2, was isolated on a multicopy plasmid. The nucleotide sequence of the DPB11 gene revealed an open reading frame predicting an 87-kDa protein. This prote...
Topics
- Amino Acid Sequence
- Cell Cycle
- Cell Cycle Proteins
- DNA Polymerase II
- DNA-Binding Proteins
- Dose-Response Relationship, Radiation
- Flow Cytometry
- Fungal Proteins
- Gene Dosage
- Genes, Fungal
- Genes, Suppressor
- Hydroxyurea
- Methyl Methanesulfonate
- Molecular Sequence Data