Article
The B subunit of the DNA polymerase alpha-primase complex in Saccharomyces cerevisiae executes an essential function at the initial stage of DNA replication.
Molecular and cellular biology - 1 Feb 1994
Foiani M, Marini F, Gamba D, Lucchini G, Plevani P
Abstract excerpt
The four-subunit DNA polymerase alpha-primase complex is unique in its ability to synthesize DNA chains de novo, and some in vitro data suggest its involvement in initiation and elongation of chromosomal DNA replication, although direct in vivo evidence for a role in the initiation reaction is st...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Antibodies, Monoclonal
- Blotting, Western
- Chromosomes, Fungal
- DNA Primase
- DNA Replication
- Genes, Fungal
- Homeostasis
- Humans
- Hydroxyurea
- Kinetics
- Macromolecular Substances
- Mice