Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The B subunit of the DNA polymerase alpha-primase complex in Saccharomyces cerevisiae executes an essential function at the initial stage of DNA replication.

Molecular and cellular biology - 1 Feb 1994

Foiani M, Marini F, Gamba D, Lucchini G, Plevani P

Abstract excerpt

The four-subunit DNA polymerase alpha-primase complex is unique in its ability to synthesize DNA chains de novo, and some in vitro data suggest its involvement in initiation and elongation of chromosomal DNA replication, although direct in vivo evidence for a role in the initiation reaction is still lacking. The function of the B subunit of the complex is unknown, but the Saccharomyces cerevisiae POL12 gene,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Amino Acid Sequence

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Antibodies, Monoclonal

Share to Genes, Fungal

Share to Kinetics

Share to Models, Genetic

Share to Molecular Sequence Data

Source

Open in PubMed Open full text

Identifiers

PMID: 8289832
DOI: 10.1128/mcb.14.2.923-933.1994
PMCID: PMC358447

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The B subunit of the DNA polymerase alpha-primase complex in Saccharomyces cerevisiae executes an essential function at the initial stage of DNA replication.PMID 8289832Read ↗

Pol12, the B subunit of DNA polymerase alpha, functions in both telomere capping and length regulation.Semantic proximity Read ↗

The B-subunit of DNA polymerase alpha-primase associates with the origin recognition complex for initiation of DNA replication.Semantic proximity Read ↗

The C-terminus of Dpb2 is required for interaction with Pol2 and for cell viability.Semantic proximity Read ↗

Distinct function of conserved amino acids in the fingers of Saccharomyces cerevisiae DNA polymerase alpha.Semantic proximity Read ↗

Fission yeast with DNA polymerase delta temperature-sensitive alleles exhibits cell division cycle phenotype.Semantic proximity Read ↗

Characterization of mutations that are synthetic lethal with pol3-13, a mutated allele of DNA polymerase delta in Saccharomyces cerevisiae.Semantic proximity Read ↗

DPB2, the gene encoding DNA polymerase II subunit B, is required for chromosome replication in Saccharomyces cerevisiae.Semantic proximity Read ↗

Dpb11, which interacts with DNA polymerase II(epsilon) in Saccharomyces cerevisiae, has a dual role in S-phase progression and at a cell cycle checkpoint.Semantic proximity Read ↗

Mutator phenotypes caused by substitution at a conserved motif A residue in eukaryotic DNA polymerase delta.Semantic proximity Read ↗

Cell cycle-dependent phosphorylation and dephosphorylation of the yeast DNA polymerase alpha-primase B subunit.Semantic proximity Read ↗

Isolation and characterization of the fission yeast gene Sprpa12+ reveals that the conserved C-terminal zinc-finger region is dispensable for the function of its product.Semantic proximity Read ↗

Compensation for the absence of the catalytically active half of DNA polymerase ε in yeast by positively selected mutations in CDC28.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.