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Article

European genetic ancestry is associated with a decreased risk of lupus nephritis.

Arthritis and rheumatism - 1 Oct 2012

Richman Ilana B, Taylor Kimberly E, Chung Sharon A, Trupin Laura, Petri Michelle, Yelin Edward, Graham Robert R, Lee Annette, Behrens Timothy W, Gregersen Peter K, Seldin Michael F, Criswell Lindsey A

Abstract excerpt

OBJECTIVE: African Americans, East Asians, and Hispanics with systemic lupus erythematosus (SLE) are more likely to develop renal disease than are SLE patients of European descent. This study was undertaken to investigate whether European genetic ancestry protects against the development of lupus nephritis, with the aim of exploring the genetic and socioeconomic factors that might explain this effect. METHODS:...

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Identifiers

PMID: 23023776
DOI: 10.1002/art.34567
PMCID: PMC3865923

Genes

BLK
STAT4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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