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Article

Genetic factors predisposing to systemic lupus erythematosus and lupus nephritis.

Seminars in nephrology - 1 Mar 2010

Ramos Paula S, Brown Elisabeth E, Kimberly Robert P, Langefeld Carl D

Abstract excerpt

Systemic lupus erythematosus (SLE) is a chronic inflammatory disease characterized by a loss of tolerance to self-antigens and the production of high titers of serum autoantibodies. Lupus nephritis can affect up to 74% of SLE patients, particularly those of Hispanic and African ancestries, and remains a major cause of morbidity and mortality. A genetic etiology in SLE is now well substantiated. Thanks to...

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Identifiers

PMID: 20347645
DOI: 10.1016/j.semnephrol.2010.01.007
PMCID: PMC2847514

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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