Article
Genetics of human lupus nephritis.
Clinical immunology (Orlando, Fla.) - 1 Dec 2017
Iwamoto Taro, Niewold Timothy B
Abstract excerpt
Systemic lupus erythematosus (SLE) is an inflammatory autoimmune disease characterized by immune complex formation with multi-organ manifestations. Lupus nephritis (LN) is one of the most severe types of organ damage in SLE, and it clearly contributes to increased morbidity and mortality due to SLE. LN occurs more frequently and is more severe in non-European ancestral backgrounds, although the cause of this...
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