Article
Systemic lupus erythematosus: association with KIR and SLC11A1 polymorphisms, ethnic predisposition and influence in clinical manifestations at onset revealed by ancestry genetic markers in an urban Brazilian population.
Lupus - 1 Mar 2011
Pedroza L S R A, Sauma M F L C, Vasconcelos J M, Takeshita L Y C, Ribeiro-Rodrigues E M, Sastre D, Barbosa C M, Chies J A B, Veit T D, Lima C P S, Oliveira L F, Henderson B L, Castro A P G, Maia M H T, Barbosa F B, Santos S E B, Guerreiro J F, Sena L, Santos E J M
Abstract excerpt
Systemic lupus erythematosus (SLE) is an autoimmune disorder of the connective tissue with a wide and heterogeneous spectrum of manifestations, with renal and neurological involvement usually related to worse prognosis. SLE more frequently affects females of reproductive age, and a high prevalence and renal manifestation seem to be associated with non-European ethnicity. The present study aims to investigate...
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